Glycomics Hits the Big Time
نویسندگان
چکیده
Cells run on carbohydrates. Glycans, sequences of carbohydrates conjugated to proteins and lipids, are arguably the most abundant and structurally diverse class of molecules in nature. Recent advances in glycomics reveal the scope and scale of their functional roles and their impact on human disease.
منابع مشابه
Parallel HITS Algorithm Implemented Using HADOOP GIRAPH Framework to resolve Big Data Problem
The Hypertext Induced Topic Search (HITS) algorithm developed by Kleinberg is a ranking technique to evaluate correlative authority and hub scores of web pages by exploring the hyperlink structure of the web. Today, the web graph has enormous size, and computing Authorities and Hub values effectively and rapidly for such massive data is truly a difficult task. In this paper, we present a parall...
متن کاملارزش تشخیصی ابزار HITS در مقایسه با ابزار CTS2 در غربالگری خشونت خانگی
Background & Aim: Violence against women is a serious social problem affecting public health. Given the relatively high prevalence of domestic violence and the need for screening, a simple tool for its correct diagnosis in a short time seems to be necessary. This study aimed to compare the diagnostic values of the HITS (Hurts, Insults, Threaten, and Screams) tool and CTS2 (Revised Conflict Tact...
متن کاملAdvancing glycomics: implementation strategies at the consortium for functional glycomics.
Glycomics-an integrated approach to study structure-function relationships of complex carbohydrates (or glycans)-is an emerging field in this age of post-genomics. Realizing the importance of glycomics, many large scale research initiatives have been established to generate novel resources and technologies to advance glycomics. These initiatives are generating and cataloging diverse data sets n...
متن کاملDevelopment and application of an algorithm to compute weighted multiple glycan alignments
Motivation A glycan consists of monosaccharides linked by glycosidic bonds, has branches and forms complex molecular structures. Databases have been developed to store large amounts of glycan-binding experiments, including glycan arrays with glycan-binding proteins. However, there are few bioinformatics techniques to analyze large amounts of data for glycans because there are few tools that can...
متن کاملشبیهسازی شار ذرات آلفای ساطعشده از دختران رادن استنشاقشده در مسیرهای هوایی استوانهای برونشیال ریه با استفاده از کد MCNPX
Biological effects of radiation are due to energy deposition arising from the alpha particles hits with cell nuclei. A simulation has been done to calculate the flux density of Radon progeny alpha particles induced from uniform inner surface source distributed in lung cylindrical airway using Monte Carlo method. Number of hits, transformation frequency and dose has been calculated using obtaine...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید
ثبت ناماگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید
ورودعنوان ژورنال:
- Cell
دوره 143 شماره
صفحات -
تاریخ انتشار 2010